Role of Coronary Calcium Score to Identify Candidates for ASCVD Prevention

Curr Atheroscler Rep. 2019 Nov 21;21(12):53. doi: 10.1007/s11883-019-0812-8.

Abstract

Purpose of review: In this review, we describe the mechanism behind coronary artery calcification formation and detection, as well as its implication in cardiovascular disease (CVD) risk stratification, intervention, and prognosis in asymptomatic individuals.

Recent findings: Multiple cohort and population studies have shown that coronary artery calcium scoring is effective and reproducible in predicting the risk for cardiovascular disease. The updated 2018 ACC/AHA guideline has incorporated consideration of coronary artery calcification testing into cardiovascular disease risk stratification and therapy guidance. Coronary artery calcification's evidence-based role in detection, risk stratification, and ultimately its unique influence on therapeutic intervention and prognosis of cardiovascular disease in asymptomatic population is increasingly being recognized..

Keywords: ASCVD; Cardiovascular disease; Coronary calcium score; Prevention.

Publication types

  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biomarkers / analysis
  • Biomarkers / metabolism
  • Calcium / analysis*
  • Calcium / metabolism
  • Coronary Artery Disease / drug therapy*
  • Coronary Artery Disease / mortality
  • Coronary Artery Disease / prevention & control*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Research Design*
  • Risk Assessment
  • Risk Factors

Substances

  • Biomarkers
  • Calcium