MRI of Cardiotoxicity

Cardiol Clin. 2019 Nov;37(4):429-439. doi: 10.1016/j.ccl.2019.07.007. Epub 2019 Aug 31.

Abstract

Cardiovascular magnetic resonance (CMR) imaging is useful to identify systolic dysfunction, particularly when echocardiographic imaging is not acceptable because of poor acoustic windows or when left ventricular ejection fraction (LVEF) is inconclusive by other modalities and an accurate LVEF measurement is needed. Of particular advantage in cardio-oncology is CMR's capability to perform tissue characterization to noninvasively identify changes in pathologic conditions related to cancer therapy or to discriminate causes of disease that may confound presentation in cardio-oncology patients. For these reasons, there is an increasing use of CMR in the screening and surveillance of cardio-oncology patients.

Keywords: Cardiotoxicity; Cardiovascular magnetic resonance; Imaging; Left ventricular ejection fraction; Myocardial strain; Tissue characterization.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Cardiotoxicity
  • Heart Diseases / chemically induced
  • Heart Diseases / diagnosis*
  • Humans
  • Magnetic Resonance Imaging, Cine / methods*
  • Myocardium / pathology*
  • Neoplasms / drug therapy*

Substances

  • Antineoplastic Agents