The ATRA-21 gene-expression model predicts retinoid sensitivity in CEBPA double mutant, t(8;21) and inv(16) AML patients

Blood Cancer J. 2019 Sep 30;9(10):76. doi: 10.1038/s41408-019-0241-5.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Biomarkers, Tumor / genetics
  • CCAAT-Enhancer-Binding Proteins / genetics*
  • Chromosome Inversion*
  • Decision Trees
  • Gene Expression Profiling
  • Gene Expression Regulation, Leukemic
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy*
  • Leukemia, Myeloid, Acute / genetics*
  • Mutation*
  • Precision Medicine
  • Predictive Value of Tests
  • Prognosis
  • Translocation, Genetic*
  • Treatment Outcome
  • Tretinoin / pharmacology*

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • CCAAT-Enhancer-Binding Proteins
  • CEBPA protein, human
  • Tretinoin