Isolated isochromosomes i(X)(p10) and idic(X)(q13) are associated with myeloid malignancies and dysplastic features

Am J Hematol. 2019 Nov;94(11):E285-E288. doi: 10.1002/ajh.25601. Epub 2019 Aug 26.
No abstract available

Publication types

  • Letter

MeSH terms

  • Age Distribution
  • Aged
  • Bone Marrow / pathology
  • Chromosomes, Human, X / genetics*
  • Chromosomes, Human, X / ultrastructure
  • DNA-Binding Proteins / genetics
  • Dioxygenases
  • Female
  • Follow-Up Studies
  • Genes, Neoplasm
  • Humans
  • Isochromosomes*
  • Leukemia, Myeloid / epidemiology
  • Leukemia, Myeloid / genetics*
  • Leukemia, Myeloid / pathology
  • Male
  • Middle Aged
  • Mutation
  • Myelodysplastic Syndromes / epidemiology
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / pathology
  • Neoplasm Proteins / genetics
  • Neoplasms, Second Primary / genetics
  • Neoplasms, Second Primary / pathology
  • Proto-Oncogene Proteins / genetics
  • Sex Distribution

Substances

  • DNA-Binding Proteins
  • Neoplasm Proteins
  • Proto-Oncogene Proteins
  • Dioxygenases
  • TET2 protein, human