Forkhead domain mutations in FOXA1 drive prostate cancer progression

Cell Res. 2019 Sep;29(9):770-772. doi: 10.1038/s41422-019-0203-2. Epub 2019 Jul 19.
No abstract available

Publication types

  • Letter

MeSH terms

  • Cell Line, Tumor
  • Chromatin / metabolism
  • Disease Progression
  • Epithelial-Mesenchymal Transition
  • Hepatocyte Nuclear Factor 3-alpha / antagonists & inhibitors
  • Hepatocyte Nuclear Factor 3-alpha / genetics
  • Hepatocyte Nuclear Factor 3-alpha / metabolism*
  • Humans
  • Male
  • Mutagenesis, Site-Directed
  • Prostatic Neoplasms / metabolism
  • Prostatic Neoplasms / pathology*
  • Protein Binding
  • RNA Interference
  • RNA, Small Interfering
  • Receptors, Androgen / metabolism
  • Signal Transduction

Substances

  • Chromatin
  • FOXA1 protein, human
  • Hepatocyte Nuclear Factor 3-alpha
  • RNA, Small Interfering
  • Receptors, Androgen