Response to Crizotinib Re-administration After Progression on Lorlatinib in a Patient With ALK-rearranged Non-small-cell Lung Cancer

Clin Lung Cancer. 2019 Sep;20(5):e555-e559. doi: 10.1016/j.cllc.2019.06.021. Epub 2019 Jun 26.
No abstract available

Keywords: ALK-TKI; MET; Mutation; NGS; Sequential treatment.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aminopyridines
  • Anaplastic Lymphoma Kinase / genetics
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Crizotinib / therapeutic use*
  • Drug Resistance, Neoplasm
  • Female
  • Gene Rearrangement
  • Humans
  • Lactams
  • Lactams, Macrocyclic / therapeutic use
  • Lung Neoplasms / drug therapy*
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrazoles
  • Treatment Outcome

Substances

  • Aminopyridines
  • Lactams
  • Lactams, Macrocyclic
  • Protein Kinase Inhibitors
  • Pyrazoles
  • Crizotinib
  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • lorlatinib