Maternal immunization is an immune strategy that protects both mothers and early-life infants from disease by the vaccination of pregnant women. The effect of maternal immunization is influenced by the types of vaccines, the timing of vaccination, the subtypes of antibodies induced by vaccines, and the health status of mothers themselves. Inactivated influenza vaccination during pregnancy and DPT vaccination during the third trimester of pregnancy have been widely used in the world, while Hepatitis B vaccine, pneumococcal and meningococcal vaccines also show good efficacy and safety in pregnant women. This article reviews the research progress of Maternal Immunization in order to provide a reference for Maternal Immunization planning and policymaking in China.
孕妇免疫接种是一种通过对孕妇实施免疫接种以保护母体及生命初期的婴儿免受疾病侵袭的免疫策略。孕妇免疫接种效果受疫苗类型、疫苗接种时机、疫苗诱导抗体亚型、母亲自身健康状况等因素影响。妊娠期间接种灭活流感疫苗以及孕晚期接种百白破疫苗已经在世界范围内广泛应用，乙型肝炎疫苗、肺炎球菌疫苗和脑膜炎球菌疫苗也在孕妇中表现出良好的有效性和安全性。本文就孕妇免疫接种的研究进展进行综述，以期为我国相关工作的开展和政策制定提供参考。.
Keywords: Infant; Pregnant women; Vaccination; Vaccines.