Magmaris™ resorbable magnesium scaffold: state-of-art review

Future Cardiol. 2019 Jul;15(4):267-279. doi: 10.2217/fca-2018-0081. Epub 2019 May 14.

Abstract

Bioresorbable scaffolds (BRS) have been advocated as the 'fourth revolution' in interventional cardiology because they could provide temporary scaffolding and then 'disappear' (resorb) potentially significantly improving coronary artery disease treatment. BRS technology has gradually matured, and there are many devices available worldwide, which are currently undergoing preclinical or clinical testing. Due to the concerns related to polylactide scaffolds, magnesium alloy is now one of the most promising resorbable technologies despite available evidences on its performances in vivo are limited to small observational studies. In this state-of-art review we present Magmaris™ (Biotronik AG, Buelach, Switzerland) magnesium-based BRS from bench to bedside, reviewing to date available clinical trial data and current recommendations for its optimal use in clinical practice.

Keywords: Magmaris™; absorb; bioresorbable scaffold; biovascular scaffold; coronary artery disease; intravascular ultrasound; optical coherence tomography.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Absorbable Implants*
  • Clinical Trials as Topic
  • Coronary Artery Disease / therapy*
  • Drug-Eluting Stents*
  • Humans
  • Magnesium*
  • Sirolimus
  • Tissue Scaffolds*

Substances

  • Magnesium
  • Sirolimus