Embolotherapy for High-Flow Arteriovenous Malformations in the Hands Using Absolute Ethanol with Coil-Assisted Dominant Outflow Vein Occlusion

J Vasc Interv Radiol. 2019 Jun;30(6):813-821. doi: 10.1016/j.jvir.2019.02.015. Epub 2019 May 3.

Abstract

Purpose: The purpose of this study was to evaluate the management, outcomes, and technical and clinical safety of coil-assisted dominant outflow vein (DOV) occlusion for the ethanol embolization of high-flow arteriovenous malformations (AVMs) in the hands.

Materials and methods: Between March 2013 and October 2016, 12 consecutive patients with AVMs with DOVs underwent ethanol embolization combined with detachable and pushable coil-assisted DOV occlusion. All patients completed the course of clinical follow-up (range: 14-57 months; mean: 36.7 months), and imaging follow-up (range: 8-25 months; mean: 16.6 months) results from the final treatment session were available for 8 patients. The therapeutic effects, degree of devascularization, and complications at the time of follow-up arteriography were evaluated as the clinical outcomes.

Results: The patients underwent 23 ethanol embolization procedures (range: 1-3; mean, 1.9) with 24 detachable coils and 223 pushable coils. The average stretched length of the total coils per patient was 320.17 cm. Seven of 12 patients (58.3%) exhibited complete responses, and 5 patients (41.7%) exhibited partial responses. Minor complications, including blistering and focal swelling, occurred in all 12 patients (100%) but showed spontaneous and complete recovery. No major complications occurred.

Conclusions: Ethanol embolization has the potential to control high-flow hand AVMs by using coil-assisted DOV occlusion with an acceptable risk of minor and major complications.

MeSH terms

  • Adolescent
  • Adult
  • Arteriovenous Malformations / diagnostic imaging
  • Arteriovenous Malformations / physiopathology
  • Arteriovenous Malformations / therapy*
  • Blood Flow Velocity
  • Child
  • Embolization, Therapeutic / adverse effects
  • Embolization, Therapeutic / instrumentation*
  • Equipment Design
  • Ethanol / administration & dosage*
  • Ethanol / adverse effects
  • Female
  • Hand / blood supply*
  • Humans
  • Male
  • Middle Aged
  • Regional Blood Flow
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome
  • Veins / abnormalities
  • Veins / diagnostic imaging
  • Veins / physiopathology*
  • Young Adult

Substances

  • Ethanol