Surgery of single ventricles in humanitarian practice: surgery for which patients?

Cardiol Young. 2019 May;29(5):583-588. doi: 10.1017/S1047951119000192. Epub 2019 May 3.

Abstract

Objectives: To analyse the feasibility and effectiveness in humanitarian practice of surgical management of children with single-ventricle heart condition.

Methods: Retrospective study of children with a single ventricle, managed by the association Mécénat-Chirurgie Cardiaque since 1996, with long-term follow-up after their return home.

Results: Of the 138 children in our cohort, 119 had one or more surgeries (180 procedures): palliative surgery alone (systemic-pulmonary anastomosis or banding), 41; partial cavo-pulmonary connection, 47; total cavo-pulmonary connection (mean age 8.5 years), 31. Operative mortality is 5.5%. After a mean follow-up of 5.6 years, 18 children (13%) were lost to follow-up. Survival at 10 years is 79% in children receiving surgery (palliative only, 72%; partial cavo-pulmonary connection, 77%; total cavo-pulmonary connection, 97%) versus 29% in children with no surgical intervention. The prognosis is better for tricuspid atresia and double-inlet left ventricle (86 and 83% survival at 10 years) than for double-outlet right ventricle or complete atrio-ventricular canal defect (64 and 68% at 5 years).

Conclusion: The surgery of the single ventricle in humanitarian medicine allows a very satisfactory survival after one or more surgeries tending towards a total cavo-pulmonary connection as soon as possible.

Keywords: CHD; Fontan; single ventricle; tricuspid atresia.

MeSH terms

  • Child
  • Child, Preschool
  • Developing Countries
  • Female
  • Follow-Up Studies
  • Fontan Procedure / methods*
  • Fontan Procedure / statistics & numerical data
  • France
  • Heart Defects, Congenital / mortality
  • Heart Defects, Congenital / surgery*
  • Heart Ventricles / abnormalities*
  • Heart Ventricles / surgery*
  • Humans
  • Male
  • Palliative Care / methods
  • Relief Work
  • Retrospective Studies
  • Risk Factors
  • Survival Rate / trends
  • Treatment Outcome