1 Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton SO16 6YD, UK; The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Isle of Wight, UK. Electronic address: g.c.roberts@soton.ac.uk.
2 Primary Care and Population Sciences, University of Southampton, Southampton, UK.