Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration

Gerardo Aguilar; Rafael Ferriols; Sara Martínez-Castro; Carlos Ezquer; Ernesto Pastor; José A Carbonell; Manuel Alós; David Navarro

doi:10.1186/s13054-019-2434-5

Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration

Crit Care. 2019 Apr 26;23(1):145. doi: 10.1186/s13054-019-2434-5.

Authors

Gerardo Aguilar^{1

2}, Rafael Ferriols^{3

4}, Sara Martínez-Castro^{5

3}, Carlos Ezquer^{3

4}, Ernesto Pastor^{5

3}, José A Carbonell^{5

3}, Manuel Alós^{3

4}, David Navarro^{3

6

7}

Affiliations

¹ Critical Care Unit, Anesthesiology and Critical Care Department, Hospital Clínico Universitario de Valencia, Valencia, Spain. gerardo.aguilar@uv.es.
² INCLIVA Health Research Institute, Avenida de Menéndez y Pelayo, 4, 46010, Valencia, Spain. gerardo.aguilar@uv.es.
³ INCLIVA Health Research Institute, Avenida de Menéndez y Pelayo, 4, 46010, Valencia, Spain.
⁴ Department of Pharmacy, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez, 17, 46010, Valencia, Spain.
⁵ Critical Care Unit, Anesthesiology and Critical Care Department, Hospital Clínico Universitario de Valencia, Valencia, Spain.
⁶ Department of Microbiology, Hospital Clínico Universitario de Valencia, Avenida Blasco Ibáñez, 17, 46010, Valencia, Spain.
⁷ School of Medicine, University of Valencia, Avenida Blasco Ibáñez, 15, 46010, Valencia, Spain.

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use
Cephalosporins / administration & dosage*
Cephalosporins / pharmacology
Cephalosporins / therapeutic use
Critical Illness / therapy
Dose-Response Relationship, Drug*
Hemofiltration / methods
Humans
Male
Tazobactam / administration & dosage*
Tazobactam / pharmacology
Tazobactam / therapeutic use

Substances

Anti-Bacterial Agents
Cephalosporins
ceftolozane, tazobactam drug combination
Tazobactam