Abstract
Historically, microsatellite instability testing has been used to identify endometrial cancer patients with Lynch Syndrome. Now, it is also being used to identify those who may be immunotherapy candidates.
Keywords:
Lynch syndrome; endometrial cancer; immunotherapy; microsatellite instability; mismatch repair deficiency.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Biomarkers, Tumor / genetics*
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Endometrial Neoplasms / diagnosis
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Endometrial Neoplasms / drug therapy
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Endometrial Neoplasms / genetics*
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Female
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Humans
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Immunotherapy / methods*
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Microsatellite Instability*
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Prognosis