Pulmonary alveolar proteinosis developing during steroid treatment in a patient with organizing pneumonia in association with atypical chronic myeloid leukemia

Chiaki Hosoda; Keisuke Saito; Shota Fujimoto; Yumie Yamanaka; Naoaki Watanabe; Hanae Miyagawa; Yusuke Kurita; Yoshitaka Seki; Akira Kinoshita; Yasuhiko Endo; Kazuyoshi Kuwano

doi:10.1002/ccr3.2014

Pulmonary alveolar proteinosis developing during steroid treatment in a patient with organizing pneumonia in association with atypical chronic myeloid leukemia

Clin Case Rep. 2019 Jan 31;7(3):477-481. doi: 10.1002/ccr3.2014. eCollection 2019 Mar.

Affiliations

¹ Department of Internal Medicine, Division of Respiratory Medicine The Jikei University Daisan Hospital Tokyo Japan.
² Department of Pathology The Jikei University School of Medicine Tokyo Japan.
³ Department of Internal Medicine, Division of Respiratory Medicine The Jikei University School of Medicine Tokyo Japan.

Abstract

Organizing pneumonia (OP) and pulmonary alveolar proteinosis (PAP) are rare complications in patients with hematologic disorders. We herein report a case of PAP that developed during steroid treatment for OP in a patient with atypical chronic myeloid leukemia. Physicians should pay close attention to these complications in patients with hematologic malignancies.

Keywords: chronic myeloid leukemia; corticosteroid therapy; organizing pneumonia; pulmonary alveolar proteinosis.

Publication types

Case Reports