Genomic analyses of microdissected Hodgkin and Reed-Sternberg cells: mutations in epigenetic regulators and p53 are frequent in refractory classic Hodgkin lymphoma

Blood Cancer J. 2019 Mar 11;9(3):34. doi: 10.1038/s41408-019-0195-7.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Biomarkers, Tumor
  • Epigenesis, Genetic
  • Female
  • Gene Expression Regulation, Neoplastic
  • Gene Frequency
  • Genomics* / methods
  • Hodgkin Disease / diagnosis*
  • Hodgkin Disease / genetics*
  • Hodgkin Disease / therapy
  • Humans
  • Male
  • Microdissection
  • Middle Aged
  • Mutation
  • Neoplasm Staging
  • Reed-Sternberg Cells / metabolism*
  • Reed-Sternberg Cells / pathology*
  • Tumor Suppressor Protein p53 / genetics
  • Young Adult

Substances

  • Biomarkers, Tumor
  • Tumor Suppressor Protein p53