Beyond protein-coding genes

Elife. 2019 Feb 19:8:e45123. doi: 10.7554/eLife.45123.

Abstract

A long non-coding RNA called lnc-NR2F1 regulates several neuronal genes, including some involved in autism and intellectual disabilities.

Keywords: autism; gene regulation; genetics; genomics; human; intellectual disabilities; long non-coding RNA; mouse; neuronal development.

MeSH terms

  • Animals
  • Autistic Disorder / genetics
  • COUP Transcription Factor I / genetics
  • Humans
  • Intellectual Disability / genetics
  • Neurons / metabolism*
  • Proteins / genetics*
  • RNA, Long Noncoding / genetics*

Substances

  • COUP Transcription Factor I
  • NR2F1 protein, human
  • Proteins
  • RNA, Long Noncoding