Hormonal imbalance and pituitary adenoma during antipsychotic treatment in an adolescent with bipolar affective disorder

Riv Psichiatr. 2019 Jan-Feb;54(1):37-39. doi: 10.1708/3104.30939.

Abstract

In this paper we present the case of a female teenager patient who was diagnosed with bipolar affective disorder and during psychotropic treatment with risperidone, the prolactin levels ranged between 55 ng/mL and 85 ng/mL at monthly repeated dosing. During this period, the patient presented somatic alterations in her state of health. The patient benefited from brain imaging, which revealed that in sella turcica is distinguished a well-defined and relatively homogeneous formation, measuring approximately 11/8 mm, suggestive of a pituitary adenoma. After changing the antipsychotic treatment, the pituitary formation resolved to a subsequent imaging re-evaluation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antipsychotic Agents / adverse effects*
  • Antipsychotic Agents / therapeutic use
  • Bipolar Disorder / complications
  • Bipolar Disorder / drug therapy*
  • Clomipramine / therapeutic use
  • Drug Substitution
  • Female
  • Haloperidol / therapeutic use
  • Humans
  • Hyperprolactinemia / chemically induced*
  • Magnetic Resonance Imaging
  • Neuroimaging
  • Olanzapine / therapeutic use
  • Pituitary Neoplasms / chemically induced*
  • Pituitary Neoplasms / complications
  • Pituitary Neoplasms / diagnostic imaging
  • Prolactin / blood
  • Prolactinoma / chemically induced*
  • Prolactinoma / complications
  • Prolactinoma / diagnostic imaging
  • Remission Induction
  • Risperidone / adverse effects*
  • Risperidone / therapeutic use

Substances

  • Antipsychotic Agents
  • Prolactin
  • Haloperidol
  • Risperidone
  • Olanzapine
  • Clomipramine