Breastfeeding by Women Living With Human Immunodeficiency Virus in a Resource-Rich Setting: A Case Series of Maternal and Infant Management and Outcomes

N Nashid; S Khan; M Loutfy; J MacGillivray; M H Yudin; D M Campbell; T Barozzino; M Baqi; S E Read; A Bitnun

doi:10.1093/jpids/piz003

Breastfeeding by Women Living With Human Immunodeficiency Virus in a Resource-Rich Setting: A Case Series of Maternal and Infant Management and Outcomes

J Pediatric Infect Dis Soc. 2020 Apr 30;9(2):228-231. doi: 10.1093/jpids/piz003.

Authors

N Nashid^{1

2}, S Khan³, M Loutfy^{4

5}, J MacGillivray^{6

7}, M H Yudin^{6

8}, D M Campbell^{2

9}, T Barozzino^{2

9}, M Baqi¹⁰, S E Read^{1

2}, A Bitnun^{1

2}

Affiliations

¹ Department of Pediatrics, The Hospital For Sick Children, Toronto, ON, Canada.
² Department of Pediatrics, University of Toronto, Toronto, ON, Canada.
³ Department of Pediatrics, Hamilton Health Sciences Centre, McMaster University, Hamilton, ON, Canada.
⁴ Department of Medicine, University of Toronto, Toronto, ON, Canada.
⁵ Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada.
⁶ Department of Obstetrics and Gynecology, St. Michael's Hospital, Toronto, ON, Canada.
⁷ Midwifery Education Program, Ryerson University, Toronto, ON, Canada.
⁸ Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON, Canada.
⁹ Department of Pediatrics, St. Michael's Hospital, Toronto, ON, Canada.
¹⁰ Department of Medicine, William Osler Health System, Toronto, ON, Canada.

PMID: 30753640
DOI: 10.1093/jpids/piz003

Abstract

The reduction in human immunodeficiency virus (HIV) transmission through breastmilk with maternal combination antiretroviral therapy (cART) has led many pregnant women living with HIV and healthcare providers to question exclusive formula feeding in resource-rich settings. Here, we describe cART prophylaxis in 3 breastfed infants whose mothers had sustained virologic suppression; all 3 of these infants remained uninfected.

Keywords: HIV; breastfeeding; child; combination antiretroviral therapy; prevention.

© The Author(s) 2019. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Publication types

Case Reports

MeSH terms

Adult
Anti-Retroviral Agents / therapeutic use*
Breast Feeding*
Drug Therapy, Combination
Female
HIV Infections / drug therapy
HIV Infections / prevention & control
HIV Infections / transmission*
Health Resources
Humans
Infant
Infectious Disease Transmission, Vertical / prevention & control*
Male
Medication Adherence
Ontario

Substances

Anti-Retroviral Agents