Development of herpes zoster during infliximab treatment for pediatric generalized pustular psoriasis: A case report

Dermatol Ther. 2019 Mar;32(2):e12838. doi: 10.1111/dth.12838. Epub 2019 Feb 17.

Abstract

The present authors report a 12-year-old Chinese child with generalized pustular psoriasis who was responded well to infliximab, but an adverse effect of herpes zoster occurred after the first infusion soon. The antiviral treatment was effective and no recurrence or flaring was observed after half-year of follow-up. This case reminds us to highlight the risk of viral infection during biological treatment on patients with psoriasis or autoimmune disease.

Keywords: generalized pustular psoriasis; herpes zoster; infliximab; pediatric.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / administration & dosage
  • Child
  • Dermatologic Agents / administration & dosage
  • Dermatologic Agents / adverse effects*
  • Follow-Up Studies
  • Herpes Zoster / chemically induced*
  • Herpes Zoster / drug therapy
  • Humans
  • Infliximab / administration & dosage
  • Infliximab / adverse effects*
  • Male
  • Psoriasis / drug therapy*
  • Psoriasis / pathology

Substances

  • Antiviral Agents
  • Dermatologic Agents
  • Infliximab