Altered NOX expression does not seem to account for epidermal NLRP3 inflammasome activation in hidradenitis suppurativa

Br J Dermatol. 2019 Aug;181(2):391-392. doi: 10.1111/bjd.17647. Epub 2019 Apr 24.

Authors

V G Frings¹, H Sennefelder¹, D Presser¹, M Goebeler¹, M Schmidt¹

Affiliation

¹ Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Josef-Schneider-Straße 2, 97076, Würzburg, Germany.

PMID: 30657189
DOI: 10.1111/bjd.17647

No abstract available

Publication types

Letter

MeSH terms

Epidermis / immunology
Epidermis / pathology*
Gene Expression Profiling
Gene Expression Regulation / immunology
Hidradenitis Suppurativa / immunology*
Hidradenitis Suppurativa / pathology
Human Umbilical Vein Endothelial Cells
Humans
Inflammasomes / immunology*
Inflammasomes / metabolism
Keratinocytes
NADPH Oxidases / analysis
NADPH Oxidases / metabolism*
NLR Family, Pyrin Domain-Containing 3 Protein / analysis
NLR Family, Pyrin Domain-Containing 3 Protein / metabolism*
Reactive Oxygen Species / immunology
Reactive Oxygen Species / metabolism
THP-1 Cells

Substances

Inflammasomes
NLR Family, Pyrin Domain-Containing 3 Protein
NLRP3 protein, human
Reactive Oxygen Species
NADPH Oxidases