Development of a Universal Influenza Vaccine

J Immunol. 2019 Jan 15;202(2):392-398. doi: 10.4049/jimmunol.1801054.

Abstract

The severity of the 2017-18 influenza season, combined with the low efficacy for some vaccine components, highlights the need to improve our current seasonal influenza vaccine. Thus, the National Institute of Allergy and Infectious Diseases recently announced a strategic plan to improve current influenza vaccines and eventually develop a "universal" influenza vaccine. This review will highlight the many different strategies being undertaken in pursuit of this goal and the exciting advances made by the influenza community. There is no doubt that an improved influenza vaccine is on the horizon.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Influenza A virus / physiology*
  • Influenza Vaccines / immunology*
  • Influenza, Human / immunology*
  • Mass Vaccination
  • National Institute of Allergy and Infectious Diseases (U.S.)
  • Quality Improvement
  • United States

Substances

  • Influenza Vaccines