[S-methylmethionin (vitamin U): experimental studies and clinical perspective]

Vopr Pitan. 2018;87(5):70-76. doi: 10.24411/0042-8833-2018-10055. Epub 2018 Sep 13.
[Article in Russian]

Abstract

Vitamin-like compound S-methyl-L-methionine (SMM, historically called vitamin U) is a metabolic agent, affects metabolic processes, which causes a wide variety of effects. The data of the studies demonstrating gastroprotective effect, hypolipidemic and antioxidant effect, participation in regulation of adipocyte function, homocysteine exchange are presented. SMM is involved in all methylation reactions in which another activated form of methionine, S-adenosylmethionine, normally participates. The results of the observed studies indicate a possible expansion of the clinical use of S-methylmethionine.

Keywords: S-methylmethionine; antioxidants; vitamin U.

Publication types

  • Review

MeSH terms

  • Adipocytes / metabolism*
  • Animals
  • Antioxidants / metabolism*
  • Gastrointestinal Agents / metabolism*
  • Homocysteine / metabolism*
  • Humans
  • Methylation
  • Vitamin U / metabolism*

Substances

  • Antioxidants
  • Gastrointestinal Agents
  • Homocysteine
  • Vitamin U