[MicroRNA and sensorineural hearing loss]

Abstract

Hearing loss caused by disorders throughout the cochlea or auditory pathway called sensorineural hearing loss. The etiology of sensorineural deafness is complex and diverse, and the sensory epithelial cell damage of the inner ear spiral is the main pathological change. MicroRNAs play a role in the regulation of gene expression by inhibiting or degrading the mRNA of target genes. More and more studies have shown that microRNA plays an important role in the development of sensorineural deafness. This article will review the process of microRNA involvement in the development of sensorineural hearing loss.

Keywords: hearing loss,sensorineural; microRNA.