XRCC2 mutation causes premature ovarian insufficiency as well as non-obstructive azoospermia in humans

Clin Genet. 2019 Mar;95(3):442-443. doi: 10.1111/cge.13475. Epub 2018 Nov 29.

Authors

Ya-Xin Zhang¹, Hai-Yu Li¹, Wen-Bin He^{1

2}, Chaofeng Tu¹, Juan Du^{1

2}, Wen Li^{1

2}, Guang-Xiu Lu^{1

2}, Ge Lin^{1

2}, Yongjia Yang³, Yue-Qiu Tan^{1

2}

Affiliations

¹ Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha, Hunan , China.
² Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan , China.
³ The Laboratory of Genetics and Metabolism, Hunan Children's Research Institute (HCRI), Hunan Children's Hospital, University of South China, Changsha, Hunan , China.

PMID: 30489636
DOI: 10.1111/cge.13475

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Azoospermia / diagnosis*
Azoospermia / genetics*
Biopsy
DNA Mutational Analysis
DNA-Binding Proteins / genetics*
Female
Genetic Association Studies
Genetic Predisposition to Disease
Humans
Male
Mutation*
Primary Ovarian Insufficiency / diagnosis*
Primary Ovarian Insufficiency / genetics*

Substances

DNA-Binding Proteins
XRCC2 protein, human