Crescendo Transient Ischemic Attacks Due to Basilar Coccidioidal Meningitis With Coccidioma

J Investig Med High Impact Case Rep. 2018 Nov 19:6:2324709618813178. doi: 10.1177/2324709618813178. eCollection 2018 Jan-Dec.

Abstract

Coccidioidal meningitis typically presents with symptoms that may include headache, altered mental status including personality changes, fever, nausea, vomiting, gait abnormalities, and focal neurological deficits. This is a case of coccidioidal meningitis that initially presented as 4 consecutive crescendo cerebrovascular transient ischemic attacks with focal neurological deficits that resolved within minutes. Imaging showed a left basilar coccidioma. Follow-up at 4 months showed treatment response to conservative therapy of fluconazole 1000 mg with a dexamethasone taper. Crescendo cerebrovascular transient ischemic attacks are a unique initial presentation of coccidioidal meningitis.

Keywords: coccidioidal meningitis; coccidioidomycosis; crescendo transient ischemic attack.