Phosphatidylinositol 3-Kinase, Growth Disorders, and Cancer

N Engl J Med. 2018 Nov 22;379(21):2052-2062. doi: 10.1056/NEJMra1704560.

Authors

Marcus D Goncalves¹, Benjamin D Hopkins¹, Lewis C Cantley¹

Affiliation

¹ From the Meyer Cancer Center (M.D.G., B.D.H., L.C.C.) and the Division of Endocrinology (M.D.G.), Department of Medicine, Weill Cornell Medicine, New York.

PMID: 30462943
DOI: 10.1056/NEJMra1704560

No abstract available

Publication types

Lecture
Review

MeSH terms

Animals
Cell Proliferation / physiology
Evolution, Molecular
Growth Disorders / metabolism
Humans
Neoplasms / drug therapy
Neoplasms / metabolism*
Oncogenes / physiology
Phosphatidylinositol 3-Kinase / physiology*
Phosphatidylinositols / chemistry
Phosphoinositide-3 Kinase Inhibitors
Signal Transduction / physiology

Substances

Phosphatidylinositols
Phosphoinositide-3 Kinase Inhibitors
Phosphatidylinositol 3-Kinase