Generation of four Isl1 reporter iPSC lines from cardiac and tail-tip fibroblasts derived from Ai6IslCre mouse

Stem Cell Res. 2018 Dec:33:125-129. doi: 10.1016/j.scr.2018.10.013. Epub 2018 Oct 11.

Abstract

Islet-1 (Isl1) is a transcription factor essential for life expressed in specific cells with different developmental origins. We have generated iPSC lines from fibroblasts of the transgenic Ai6 x Isl1-Cre (Ai6IslCre) mouse. Here we describe the complete characterization of four iPSC lines: ATCi-Ai6IslCre10, ATCi-Ai6IslCre35, ATCi-Ai6IslCre74 and ATCi-Ai6IslCre80.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Differentiation
  • Fibroblasts / metabolism
  • Induced Pluripotent Stem Cells / metabolism
  • LIM-Homeodomain Proteins / genetics*
  • Mice
  • Transcription Factors / genetics*

Substances

  • LIM-Homeodomain Proteins
  • Transcription Factors
  • insulin gene enhancer binding protein Isl-1