Abstract
Gastrointestinal stromal tumour (GIST) is a subtype of sarcoma that may occur in any part of the gastrointestinal system, most frequently in the stomach and small intestine. The most common symptoms are bleeding and abdominal pain. In this clinical review, we summarise the progress made with this condition and discuss the recommended diagnostics and treatment of GIST.
MeSH terms
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Antineoplastic Agents / therapeutic use
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Combined Modality Therapy
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Gastrointestinal Neoplasms* / diagnosis
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Gastrointestinal Neoplasms* / genetics
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Gastrointestinal Neoplasms* / pathology
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Gastrointestinal Neoplasms* / therapy
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Gastrointestinal Stromal Tumors* / diagnosis
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Gastrointestinal Stromal Tumors* / genetics
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Gastrointestinal Stromal Tumors* / pathology
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Gastrointestinal Stromal Tumors* / therapy
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Humans
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Imatinib Mesylate / therapeutic use
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Mutation
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Proto-Oncogene Proteins c-kit / genetics
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Receptor, Platelet-Derived Growth Factor alpha / genetics
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Tomography, X-Ray Computed
Substances
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Antineoplastic Agents
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Imatinib Mesylate
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Proto-Oncogene Proteins c-kit
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Receptor, Platelet-Derived Growth Factor alpha