Data on uncoupling protein-3 levels, hypoxia, low flow ischemia, and insulin stimulation in dystrophin-deficient mdx mouse hearts

Wen Zhang; A Elizabeth Sang; Michiel Ten Hove; Stefan Neubauer; Kieran Clarke

doi:10.1016/j.dib.2018.08.010

Data on uncoupling protein-3 levels, hypoxia, low flow ischemia, and insulin stimulation in dystrophin-deficient mdx mouse hearts

Data Brief. 2018 Aug 8:20:277-280. doi: 10.1016/j.dib.2018.08.010. eCollection 2018 Oct.

Authors

Wen Zhang¹, A Elizabeth Sang¹, Michiel Ten Hove², Stefan Neubauer², Kieran Clarke¹

Affiliations

¹ Department of Physiology, Anatomy and Genetics, University of Oxford, Sherrington Building, Parks Road, Oxford OX1 3PT, United Kingdom.
² Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.

Abstract

The data contain body weights, plasma free fatty acids concentrations and cardiac uncoupling protein-3 protein levels for wild-type and mdx mice. The data provide heart rates, left ventricular contractile functions, coronary flow, phosphocreatine concentrations, and adenosine 5'-triphosphate (ATP) concentrations throughout hypoxia in mdx mouse hearts. This data article also provides left ventricular contractile functions after low flow ischemia with and without glucose, glycogen levels before ischemia or hypoxia, glucose uptake rates during low flow ischemia and insulin stimulation, and insulin-stimulated phospho-Akt protein levels, a protein in insulin signaling, in mdx mouse hearts.