Gender differences in diabetes self-care in adults with type 1 diabetes: Findings from the T1D Exchange clinic registry

J Diabetes Complications. 2018 Oct;32(10):961-965. doi: 10.1016/j.jdiacomp.2018.08.009. Epub 2018 Aug 10.

Abstract

Aims: To evaluate gender differences in diabetes self-care components including glycemic, blood pressure and lipid control, utilization of diabetes technologies and acute diabetes complications in adults with type 1 diabetes.

Methods: A total of 9,481 participants >18 years were included in the analysis, 53% were female. Variables of interest included glycemic control measured by HbA1c, systolic/diastolic blood pressures, presence of dyslipidemia, insulin delivery modality, and rates of acute complications.

Results: Glycemic control was similar in women and men (mean HbA1c in both groups: 8.1% ± 1.6% (64 ± 16 mmol/mol), (p = 0.54). More women used insulin pump therapy (66% vs. 59%, p < 0.001) but use of sensor technology was similar (p < = 0.42). Women had higher rates of diabetic ketoacidosis (DKA) (5% vs. 3%, p < 0.001) and eating disorders (1.7% vs. 0.1%, p < 0.001). Severe hypoglycemia rates were not different between men and women (p = 0.42). Smoking (6% vs 4%, p < 0.001), systolic (125 ± 14.2 vs. 121 ± 14.4, p < 0.001) and diastolic blood pressure (73.3 ± 9.5 vs. 72.2 ± 9.3, p < 0.001) and rate of dyslipidemia (28% vs. 23%, p < 0.001) were higher in men.

Conclusion: While glycemic control in type 1 diabetes was similar regardless of gender, rates of DKA and eating disorders were higher in women while rates of smoking, hypertension and dyslipidemia were higher in men.

Keywords: Cardiovascular risk factors; Diabetes self-management; Eating disorder; Gender; Type 1 diabetes (T1D).

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology
  • Diabetes Mellitus, Type 1 / epidemiology*
  • Diabetes Mellitus, Type 1 / therapy*
  • Diabetic Angiopathies / epidemiology
  • Feeding and Eating Disorders / epidemiology
  • Feeding and Eating Disorders / etiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Registries
  • Retrospective Studies
  • Risk Factors
  • Self Care / standards
  • Self Care / statistics & numerical data*
  • Sex Characteristics
  • Sex Factors
  • Young Adult