Aneurysmal fibrous histiocytomas with recurrent rearrangement of the PRKCD gene and LAMTOR1-PRKCD fusions

J Cutan Pathol. 2018 Dec;45(12):966-968. doi: 10.1111/cup.13339. Epub 2018 Sep 5.
No abstract available

Keywords: LAMTOR1-PRKCD fusion; aneurysmal dermatofibroma; aneurysmal fibrous histiocytoma; next-generation sequencing.

MeSH terms

  • Carrier Proteins* / genetics
  • Carrier Proteins* / metabolism
  • Female
  • Gene Rearrangement*
  • Histiocytoma, Benign Fibrous* / genetics
  • Histiocytoma, Benign Fibrous* / metabolism
  • Histiocytoma, Benign Fibrous* / pathology
  • Humans
  • Intracellular Signaling Peptides and Proteins
  • Male
  • Oncogene Proteins, Fusion* / genetics
  • Oncogene Proteins, Fusion* / metabolism
  • Protein Kinase C-delta* / genetics
  • Protein Kinase C-delta* / metabolism
  • Skin Neoplasms* / genetics
  • Skin Neoplasms* / metabolism
  • Skin Neoplasms* / pathology

Substances

  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • LAMTOR1 protein, human
  • Oncogene Proteins, Fusion
  • PRKCD protein, human
  • Protein Kinase C-delta