A Novel Homozygous Mutation With Different Clinical Presentations in 2 IRAK-4-Deficient Siblings: First Case With Recurrent Salmonellosis and Non-Hodgkin Lymphoma

Affiliations

• ¹ Baskent University Faculty of Medicine, Department of Pediatric Allergy and Immunology, Konya, Turkey.
• ² Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Paris, France.
• ³ St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, USA.
• ⁴ Paris Descartes University, Imagine Institute, Paris, France.
• ⁵ Pediatric Hematology-Immunology Unit, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris AP-HP, Paris, France.
• ⁶ Howard Hughes Medical Institute, New York, USA.
• ⁷ Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, France.
• ⁸ Hacettepe University Ihsan Dogramacı Children's Hospital, Department of Pediatric Immunology, Ankara, Turkey.
• ⁹ Ankara University Medical School, Department of Pediatric Infectious Diseases, Ankara, Turkey.
• ¹⁰ Konya Training and Research Hospital, Department of Pediatric Nephrology, Konya, Turkey.
• ¹¹ Necmettin Erbakan University Meram Medical Faculty, Department of Pediatrics, Division of Pediatric Allergy and Immunology, Konya, Turkey.