Fast-track versus long-term hospitalizations for patients with non-disabling acute ischaemic stroke

Eur J Neurol. 2019 Jan;26(1):51-e4. doi: 10.1111/ene.13761. Epub 2018 Sep 3.

Abstract

Background and purpose: The aim was to assess the feasibility and safety of fast-track hospitalizations in a selected cohort of patients with stroke.

Methods: Patients hospitalized at the Stroke Center of the University Hospital Basel, Switzerland, with an acute ischaemic stroke confirmed on magnetic resonance diffusion-weighted imaging were included. Neurological deficits of the included patients were non-disabling, i.e. not interfering with activities of daily living and compatible with a direct discharge home. Patients with premorbid disability were excluded. All patients were admitted to the Stroke Center for ≥24 h. Two study groups were compared - fast-track hospitalizations (≤72 h) and long-term hospitalizations (>72 h). The primary end-point was a composite of any unplanned rehospitalization for any reason within 3 months since hospital discharge and a modified Rankin Scale 3-6 at 3 months. Adjustment for confounders was done using the inverse probability of treatment weights (IPTW).

Results: Amongst the 521 patients who met the inclusion criteria, fast-track hospitalizations were performed in 79 patients (15%). In the fast-track group, seven patients (8.9%) met the primary end-point, compared to 37 (8.4%) in the long-term group [odds ratio (OR) 1.06, 95% confidence interval (CI) 0.42-2.34, P = 0.88]. After weighting for IPTW, the odds of the primary end-point remained similar between the two arms (ORIPTW 1.27, 95% CI 0.51-3.16, P = 0.61). The costs of fast-track hospitalizations were lower, on average, by $4994.

Conclusions: Fast-track hospitalizations including a full workup proved to be feasible, showed no increased risk and were less expensive than long-term hospitalizations.

Keywords: hospitalization; stroke; treatment outcome.

Publication types

  • Comparative Study

MeSH terms

  • Activities of Daily Living
  • Aged
  • Brain Ischemia / diagnostic imaging
  • Brain Ischemia / economics
  • Brain Ischemia / therapy*
  • Cohort Studies
  • Diffusion Magnetic Resonance Imaging
  • Disability Evaluation
  • Feasibility Studies
  • Female
  • Hospital Costs
  • Hospitalization* / economics
  • Hospitalization* / statistics & numerical data
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Patient Readmission / statistics & numerical data
  • Retrospective Studies
  • Stroke / diagnostic imaging
  • Stroke / economics
  • Stroke / therapy*
  • Switzerland
  • Treatment Outcome