Objective: To explore the trends and distribution of chronic obstructive pulmonary disease (COPD) mortality of the residents with different characteristics from 2000 to 2016 in Tianjin. Methods: COPD mortality data in 2000-2016 were from Tianjin population based mortality surveillance system. The mortality rate of COPD, difference in the rate by gender, age, and geographic distribution, and the trend over years were analyzed. Age-sex-standardized mortality rates of COPD were calculated using the year 2000 world standard population. Joinpoint regression and Cochran-Armitage trend analysis were used to examine the trend of mortality. Results: The crude COPD mortality rate in Tianjin decreased from 57.57/100 000 in 2000 to 28.23/100 000 in 2016 (annual percent change (APC)=-5.01%, Z=-64.76, P<0.001), and the standardized mortality rate decreased from 56.53/100 000 in 2000 to13.88/100 000 in 2016 (APC=-9.17%, Z=-100.83, P<0.001). The crude COPD mortality rate of males decreased from 54.57/100 000 to 27.77/100 000 (APC=-4.89%, Z=-43.63, P<0.001) and the standardized mortality rate decreased from 57.52/100 000 to 14.63/100 000 (APC=-9.07%, Z=-71.48, P<0.001). The crude COPD mortality rate of females decreased from 60.63/100 000 to 28.68/100 000 (APC=-5.12%, Z=-47.92, P<0.001) and the standardized mortality rate decreased from 55.53/100 000 to 13 13/100 000 (APC=-9.27%, Z=-71.13, P<0.001). The crude mortality rate of COPD in urban areas decreased from 45.07/100 000 to 19.54/100 000 (APC=-5.35%, Z=-42.38, P<0.001) and the standardized mortality rate decreased from 39.24/100 000 to 7.45/100 000 (Z=-63.97, P<0.001, APC=-10.22%). The crude mortality rate of COPD in rural areas decreased from 70.20/100 000 to 37.24/100 000 (APC=-4.77%, Z=-48.77, P<0.001) and the standardized mortality rate decreased from 78.88/100 000 to 25.70/100 000 (APC=-7.59%, Z=-72.43, P<0.001). The COPD mortality rate in rural areas was higher than that in urban areas (P<0.001). The COPD mortality rate in 35 years old and over decreased from 2000 to 2016 (P<0.001). Conclusion: The COPD mortality in Tianjin decreased from 2000 to 2016. More efforts are need to reduce COPD mortality in Tianjin, in particular people in rural areas.
目的： 了解2000-2016年天津市居民慢性阻塞性肺疾病（COPD）死亡率及其变动趋势。 方法： 采用天津市全死因监测管理系统收集2000-2016年天津市居民COPD死亡情况，统计天津市居民COPD死亡率，比较不同年龄、性别以及地区之间死亡率的差异，并分析其变化趋势。采用2000年世界标准人口计算年龄别、性别标化死亡率。采用Joinpoint回归和Cochran-Armitage趋势检验进行趋势分析。 结果： 2000-2016年COPD死亡率为57.57/10万~28.23/10万，呈下降趋势[年度变化百分比（APC）=-5.01%；Z=-64.76，P<0.001]；标化死亡率为56.53/10万~13.88/10万，呈下降趋势（APC=-9.17%，Z=-100.83，P<0.001）。2000-2016年男性COPD死亡率为54.57/10万~27.77/10万，呈下降趋势（APC=-4.89%，Z=-43.63，P<0.001）；标化死亡率为57.52/10万~14.63/10万，呈下降趋势（APC=-9.07%，Z=-71.48，P<0.001）。2000-2016年女性COPD死亡率为60.63/10万~28.68/10万，呈下降趋势（APC=-5.12%，Z=-47.92，P<0.001）；标化死亡率为55.53/10万~13.13/10万，呈下降趋势（APC=-9.27%，Z=-71.13，P<0.001）。2000-2016年天津市城市COPD死亡率为45.07/10万~19.54/10万，呈下降趋势（APC=-5.35%，Z=-42.38，P<0.001）；标化死亡率为39.24/10万~7.45/10万，呈下降趋势（APC=-10.22%，Z=-63.97，P<0.001）。2000-2016年天津市农村COPD死亡率为70.20/10万~37.24/10万，呈下降趋势（APC=-4.77%，Z=-48.77，P<0.001）；标化死亡率为78.88/10万~25.70/10万，呈下降趋势（APC=-7.59%，Z=-72.43，P<0.001）。各年份农村COPD死亡率均明显高于城市地区（P<0.001）。2000-2016年，除了<35岁组，其他各年龄组COPD死亡率均呈下降趋势（P<0.001）。 结论： 2000-2016年期间天津市居民COPD死亡率呈明显的下降趋势特点。农村人群为COPD死亡高发人群。.
Keywords: Epidemiology; Mortality; Pulmonary disease, chronic obstructive; Surveillance.