Myocardial Viability Testing to Guide Coronary Revascularization

Interv Cardiol Clin. 2018 Jul;7(3):355-365. doi: 10.1016/j.iccl.2018.03.005. Epub 2018 Jun 29.

Abstract

Left ventricular dysfunction remains one of the best prognostic determinants of survival in patients with coronary artery disease. Revascularization has been shown to improve survival compared with medical therapy alone. Viability testing can help direct patients who will benefit the most from revascularization. Single-photon emission computed tomography, dobutamine stress echo, cardiac MRI, and PET imaging with F18-fluorodeoxyglucose are the most common modalities for assessing myocardial viability. Viability testing can help differentiate which patients benefit most from chronic total occlusion interventions.

Keywords: Chronic total occlusion; Hibernation; Revascularization; Viability.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Chronic Disease
  • Coronary Occlusion / diagnosis
  • Coronary Occlusion / surgery
  • Echocardiography, Stress
  • Fluorodeoxyglucose F18
  • Heart Failure / diagnosis
  • Heart Failure / surgery
  • Humans
  • Magnetic Resonance Angiography
  • Myocardial Revascularization / methods*
  • Myocardial Stunning / diagnosis
  • Myocardial Stunning / surgery*
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Tissue Survival
  • Tomography, Emission-Computed, Single-Photon
  • Ventricular Dysfunction, Left / diagnosis
  • Ventricular Dysfunction, Left / surgery

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18