Spinal anesthesia for surgery longer than 60 min in infants: experience from the first 2 years of a spinal anesthesia program

J Anesth. 2018 Aug;32(4):637-640. doi: 10.1007/s00540-018-2517-5. Epub 2018 May 28.

Abstract

Purpose: Spinal anesthesia (SA) is being increasingly used in infants to avoid the potential negative neurocognitive effects of general anesthesia (GA). However, SA has been reported to provide a relatively short duration of surgical anesthesia.

Methods: We retrospectively reviewed SA cases for surgical procedures lasting more than 60 min in children up to 3 years old. All patients received bupivacaine 0.5% (1 mg/kg up to 7 mg) with clonidine 1 µg/kg ± epinephrine. The primary outcome was success of SA without subsequent conversion to GA.

Results: Thirty-five patients met inclusion criteria (all males, age 7 ± 5 months, weight 8 ± 2 kg). Procedures included male genital, groin and multiple site surgeries. Average surgical duration was 71 ± 12 min (range 60-111 min). SA was successful in 31 of 35 patients (89%; 95% confidence interval 78, 99%). The cause of failure was rarely due to the duration of surgery (1 of 4 patients). Six patients with successful SA required sedation with dexmedetomidine ± fentanyl. Differences in procedure duration and patient characteristics were not statistically significant between successful and failed SA.

Conclusions: SA is a highly successful technique and may offer an alternative to GA in children undergoing appropriate surgery expected to last as long as 60-100 min.

Keywords: Children; Clonidine; Epinephrine; Spinal anesthesia.

MeSH terms

  • Anesthesia, General / methods*
  • Anesthesia, Spinal / methods*
  • Body Weight
  • Bupivacaine / administration & dosage*
  • Clonidine / administration & dosage*
  • Dexmedetomidine / administration & dosage
  • Fentanyl / administration & dosage
  • Humans
  • Infant
  • Male
  • Retrospective Studies
  • Time Factors

Substances

  • Dexmedetomidine
  • Clonidine
  • Fentanyl
  • Bupivacaine