Diagnostic serum vitamin D level is not a reliable prognostic factor for resectable breast cancer

Future Oncol. 2018 Jun;14(15):1461-1467. doi: 10.2217/fon-2017-0608. Epub 2018 May 9.

Abstract

Aim: There are inconsistent results about the effects of vitamin D level on breast cancer prognosis. We aimed to investigate the effect of vitamin D levels on the prognosis of resectable breast cancer in a patient group with highly different clothing styles.

Patients & methods: A total of 186 breast cancer patients were enrolled in the study.

Results: Vitamin D level was sufficient, insufficient and deficient in 17.2, 52.2 and 30.6% of patients, respectively. There was a significant relationship between clothing style and serum 25 (OH) D levels. We could not establish any relation between vitamin D level and tumor characteristics or survival.

Conclusion: Vitamin D supplementation can be more important than diagnostic serum vitamin D level on prognosis of breast cancer.

Keywords: prognosis; resectable breast cancer; vitamin D.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents / therapeutic use
  • Breast / pathology
  • Breast / surgery
  • Breast Neoplasms / blood*
  • Breast Neoplasms / mortality
  • Breast Neoplasms / pathology
  • Breast Neoplasms / therapy
  • Chemotherapy, Adjuvant
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Mastectomy
  • Middle Aged
  • Neoplasm Recurrence, Local / blood
  • Neoplasm Recurrence, Local / epidemiology*
  • Neoplasm Recurrence, Local / pathology
  • Prognosis
  • Reproducibility of Results
  • Treatment Outcome
  • Turkey
  • Vitamin D / blood*
  • Vitamin D / therapeutic use
  • Young Adult

Substances

  • Antineoplastic Agents
  • Vitamin D