Background: Those with mild cognitive impairment (MCI) are ten times more like to develop Alzheimer's disease (AD) than the general population. MCI diagnosis and early intervention are helpful for the diagnosis and treatment of AD in its early stages, thus delaying its development and improving the quality of life for those with MCI.
Aims: To analyze the relationship between the lifestyle of the elderly in Shanghai communities and mild cognitive impairment and to look for preventative lifestyle measures for the elderly with mild cognitive impairment.
Methods: 1005 elderly persons were randomly selected from the community in Shanghai. Study participants were 265 people with an MCI diagnosis and 607 non-MCI elderly persons. The demographic and lifestyle data of these elderly people were collected for univariate and multivariate analysis to search for statistically significant indicators.
Results: The univariate analysis revealed that smoking (χ2 = 10.808, p=0.001), tea drinking (χ2 =11.74, p= 0.001), having hobbies (χ2 = 20.815, p<0.001), reading (χ2 =28.670, p= 0.001), surfing the internet (χ2 =12.623, p= 0.001), and photography (χ2 =4.470, p= 0.034) were protective factors for MCI. The binary logistic regression, a multivariate analysis, revealed that smoking, reading, and surfing the internet had statistical significance. Their OR values were 0.562 (0.358-0.883), 0.428 (0.253-0.726), and 0.238 (0.071-0.797) respectively. Thus, smoking, reading, and surfing the internet were protective factors for MCI.
Conclusions: Lifestyle is associated with the onset of MCI. Good life habits and behaviors are significant in the prevention of MCI developing into Alzheimer's.
背景: 轻度认知功能损害（Mild cognitive impairment，MCI）老人发展为阿尔茨海默病（Alzheimer’s disease，AD）的风险比普通人群高10 倍。对MCI 诊断及早期干预有助于早期诊治AD，从而延缓其发展，改善MCI老人的生活质量。.
目的: 分析上海社区老人生活方式与轻度认知损害的关系，从生活方式中寻找老年轻度认知损害的防治措施。.
方法: 随机抽取1005 名上海社区老人，最终确诊的265 名MCI 和607 名正常老人作为研究对象，搜集这些老人的人口学、生活习惯等资料，进行单因素和多因素分析，寻找有统计学意义的指标。.
结果: 单因素分析发现吸烟（χ2= 10.808, p=0.001）、饮茶（χ2=11.74, p= 0.001）、有业余爱好（χ2= 20.815,p<0.001）、读书（χ2=28.670, p= 0.001）、上网（χ2=12.623,p= 0.001）、摄影（χ2=4.470, p= 0.034）为MCI 的保护性因素。多因素分析二项分类logistic 回归分析发现，吸烟、读书、上网有统计学意义，其OR 值分别为0.562(0.358-0.883)、0.428 (0.253-0.726)、0.238 (0.071-0.797)。即吸烟、读书、上网为MCI 的保护性因素。.
结论: 生活方式和MCI 的发病相关，良好的生活习惯及行为方式对预防MCI 有积极意义。.
Keywords: lifestyle; mild cognitive impairment; protective factors.