RETRACTED: MicroRNA-30b promotes lipopolysaccharide-induced inflammatory injury and alleviates autophagy through JNK and NF-κB pathways in HK-2 cells

Biomed Pharmacother. 2018 May:101:842-851. doi: 10.1016/j.biopha.2018.02.085. Epub 2018 Mar 22.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief as there are concerns about the reliability of the results included in the article. The journal was initially contacted by the first author to request the retraction as they reported that results were not reproducible post publication. Also, the author acknowledged that the corresponding authors were not aware of the submission of this article. Given the comments of Dr Elisabeth Bik https://scienceintegritydigest.com/2020/02/21/the-tadpole-paper-mill/ regarding this article, the journal requested the author to provide the raw data. However, the author was not able to fulfil this request.

Keywords: Acute kidney injury; Inflammatory injury; JNK signaling pathway; Lipopolysaccharide; MicroRNA-30b; NF-κB signaling pathway.

Publication types

  • Retracted Publication

MeSH terms

  • Animals
  • Apoptosis
  • Autophagy / genetics*
  • Cell Line
  • Cell Survival
  • Cytokines / metabolism
  • Humans
  • Inflammation / pathology*
  • Lipopolysaccharides
  • MAP Kinase Signaling System*
  • Male
  • Mice, Inbred C57BL
  • MicroRNAs / genetics
  • MicroRNAs / metabolism*
  • NF-kappa B / metabolism*

Substances

  • Cytokines
  • Lipopolysaccharides
  • MIRN30b microRNA, human
  • MicroRNAs
  • Mirn30d microRNA, mouse
  • NF-kappa B