Sending Cancer into the Fetal Position

Hannah A Pizzato; Deepta Bhattacharya

doi:10.1016/j.stem.2018.03.007

Sending Cancer into the Fetal Position

Cell Stem Cell. 2018 Apr 5;22(4):479-480. doi: 10.1016/j.stem.2018.03.007.

Authors

Hannah A Pizzato¹, Deepta Bhattacharya²

Affiliations

¹ Division of Biological and Biomedical Sciences, Washington University in St. Louis, Saint Louis, MO 63110, USA; Department of Immunobiology, University of Arizona College of Medicine, Tucson, AZ 85724, USA.
² Department of Immunobiology, University of Arizona College of Medicine, Tucson, AZ 85724, USA. Electronic address: deeptab@email.arizona.edu.

PMID: 29625065
DOI: 10.1016/j.stem.2018.03.007

Abstract

Malignant cells gain the ability to self-renew and reacquire expression of proteins associated with embryonic development. In this issue of Cell Stem Cell, Kooreman et al. (2018) demonstrate that vaccination of mice with syngeneic inactivated iPSCs generates T cell immunity against embryonic antigens and provides resistance to several different types of cancers.

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MeSH terms

Animals
Immunity
Induced Pluripotent Stem Cells / immunology*
Mice
Neoplasms*
T-Lymphocytes / immunology
Vaccines*

Substances

Vaccines