Transactivator: A New Face of Arabidopsis AGO1

Dev Cell. 2018 Feb 5;44(3):277-279. doi: 10.1016/j.devcel.2018.01.014. Epub 2018 Feb 5.

Abstract

Argonaute (AGO) proteins execute RNA-induced transcriptional and post-transcriptional gene silencing. In this issue of Developmental Cell, Liu et al. (2018) uncover a nuclear function for Arabidopsis AGO1 in positively regulating gene expression. AGO1, guided by small RNAs, binds to chromatin to induce target gene transcription in response to environmental stimuli.

Publication types

  • Comment

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis Proteins / genetics*
  • Argonaute Proteins / genetics
  • MicroRNAs
  • RNA Interference
  • Trans-Activators

Substances

  • AGO1 protein, Arabidopsis
  • Arabidopsis Proteins
  • Argonaute Proteins
  • MicroRNAs
  • Trans-Activators