Lateral retropharyngeal lymph node metastasis from squamous cell carcinoma of the upper gingiva: A case report

Mol Clin Oncol. 2018 Jan;8(1):68-72. doi: 10.3892/mco.2017.1496. Epub 2017 Nov 13.

Abstract

Lateral retropharyngeal lymph node (LRPLN) is located between the internal carotid artery and the prevertebral muscles. Metastasis to the LRPLN is frequent in nasopharyngeal cancer, but is rare in oral cancer. The prognosis of patients with oral cancer with LRPLN metastasis is usually poor. The present study reported a patient with LRPLN metastasis from squamous cell carcinoma of the upper gingiva, who survived for >7 years. Docetaxel, cisplatin and fluorouracil (TPF) therapy was performed as induction chemotherapy and it was planned to subsequently conduct chemoradiotherapy or surgery. As the tumor only exhibited a transient response to TPF, surgery was selected. Postoperatively, only radiotherapy was performed and a favorable outcome was achieved.

Keywords: induction chemotherapy; lateral retropharyngeal lymph node; metastasis; oral cancer.