Use of quantitative ultrasound as bone mineral density evaluation in an Italian female population living with HIV: A real-life experience

J Women Aging. 2019 Mar-Apr;31(2):176-188. doi: 10.1080/08952841.2018.1428100. Epub 2018 Jan 25.

Abstract

This is a multicenter cross-sectional study where we aimed to detect the rate of osteopenia/osteoporosis in an HIV female population (WLWHIV) by means of "heel quantitative ultrasound" (QUS) measurement. We enrolled 273 patients, mean age 48.1 years, 36% menopausal, 96% on combination antiretroviral therapy (cART). Calcaneal measure of bone mass index by QUS revealed osteopenia and osteoporosis in 76 (27.8%) and 16 (5.9%) WLWHIV. Our data underline the correlation between low QUS parameters and traditional risk factors for osteoporosis rather than with cART exposure, thus suggesting the crucial importance of detection and correction of traditional risk factors for osteoporosis in WLWHIV.

Keywords: Osteopenia; QUS; Sahara; osteoporosis; vitamin D; women living with HIV.

Publication types

  • Multicenter Study

MeSH terms

  • Aged
  • Bone Density
  • Bone Diseases, Metabolic / diagnostic imaging*
  • Bone Diseases, Metabolic / epidemiology
  • Bone Diseases, Metabolic / virology
  • Calcaneus / diagnostic imaging*
  • Cross-Sectional Studies
  • Female
  • HIV
  • HIV Infections / complications
  • HIV Infections / diagnostic imaging*
  • Humans
  • Italy / epidemiology
  • Middle Aged
  • Osteoporosis / diagnostic imaging*
  • Osteoporosis / epidemiology
  • Osteoporosis / virology
  • Risk Factors
  • Ultrasonography / methods*