Go, no-go decision making for phase 3 clinical trials: ACT IV revisited - Authors' reply

Affiliations

• ¹ Department of Neurology, University Hospital and University of Zurich, Zurich, Switzerland. Electronic address: michael.weller@usz.ch.
• ² Department of Neurological Surgery, University of California, San Francisco, CA, USA.
• ³ Washington University, St Louis, MO, USA.
• ⁴ Stanford University Medical Center, Palo Alto, CA, USA.
• ⁵ The Johns Hopkins Hospital, Baltimore, MD, USA.
• ⁶ Juravinski Cancer Centre, Hamilton, ON, Canada.
• ⁷ Barrow Neurological Institute, Phoenix, AZ, USA.
• ⁸ DENT Neurologic Institute, Buffalo, NY, USA.
• ⁹ John Theurer Cancer Center, Hackensack, NJ, USA.
• ¹⁰ Columbia University Medical Center, New York, NY, USA.
• ¹¹ University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
• ¹² Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
• ¹³ Westmead Hospital, Westmead, NSW, Australia.
• ¹⁴ University of Calgary, Department of Clinical Neurosciences, Division of Neurosurgery, Foothills Hospital, Calgary, AB, Canada.
• ¹⁵ Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.
• ¹⁶ Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
• ¹⁷ The University of Heidelberg and German Cancer Research Center, Heidelberg, Germany.
• ¹⁸ Celldex Therapeutics, Inc, Hampton, NJ, USA.
• ¹⁹ Department of Oncology, University Hospital and University of Zurich, Zurich, Switzerland.
• ²⁰ The Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, NC, USA.