Functional analysis of the GRMZM2G174449 promoter to identify Rhizoctonia solani-inducible cis-elements in maize

BMC Plant Biol. 2017 Dec 4;17(1):233. doi: 10.1186/s12870-017-1181-5.

Abstract

Background: Banded leaf and sheath blight (BLSB), caused by the necrotrophic fungus Rhizoctonia solani, is a highly devastating disease in most maize and rice growing areas of the world. However, the molecular mechanisms of perceiving pathogen signals are poorly understood in hosts.

Results: Here, we identified a Rhizoctonia solani-inducible promoter pGRMZM2G174449 in maize. Deletion analysis showed that the -574 to -455 fragment was necessary for pGRMZM2G174449 in responding to R. solani and this fragment contained the unknown pathogen-inducible cis-elements according to the bioinformatics analysis. Furthermore, detailed quantitative assays showed that two cis-elements, GCTGA in the -567 to -563 region and TATAT in the -485 to -481 region, were specifically responsible for the R. solani-inducible activity. A series of point mutation analysis indicated that the two cis-elements have the conserved motifs of NHWGN and DWYWT, respectively.

Conclusion: Our results indicated that pGRMZM2G174449 is a good R. solani-inducible promoter suitable for genetic engineering of BLSB resistance. And NHWGN and DWYWT are two R. solani-inducible cis-elements that play important roles in pGRMZM2G174449 responding to R. solani.

Keywords: Banded leaf and sheath blight; Genetic engineering; Maize; Rhizoctonia solani; cis-element.

MeSH terms

  • DNA, Plant
  • Disease Resistance / genetics
  • Gene Expression Profiling
  • Gene Expression Regulation, Plant*
  • Oryza / genetics
  • Plant Diseases / genetics*
  • Plant Diseases / microbiology
  • Plants, Genetically Modified
  • Promoter Regions, Genetic*
  • Rhizoctonia / physiology
  • Zea mays / genetics*
  • Zea mays / microbiology

Substances

  • DNA, Plant