"Mouse-MRD" in central nervous system acute lymphoblastic leukaemia: assessing bone marrow minimal residual disease using a xenograft model - from bedside to the bench and back again

Br J Haematol. 2018 Nov;183(4):686-688. doi: 10.1111/bjh.15024. Epub 2017 Nov 28.

Authors

Julia Alten¹, Alexander Claviez¹, Simon Vieth¹, Gunnar Cario¹, Denis M Schewe¹

Affiliation

¹ Paediatric Haematology/Oncology, Christian Albrechts University Kiel and University Hospital Schleswig-Holstein, Kiel, Germany.

PMID: 29193025
DOI: 10.1111/bjh.15024

No abstract available

Keywords: acute lymphoblastic leukaemia; central nervous system relapse; minimal residual disease; xenograft.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Bone Marrow* / metabolism
Bone Marrow* / pathology
Central Nervous System Neoplasms* / metabolism
Central Nervous System Neoplasms* / pathology
Child
Female
Heterografts
Humans
Mice
Neoplasm Transplantation
Neoplasm, Residual
Neoplasms, Experimental* / metabolism
Neoplasms, Experimental* / pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma* / pathology