Dominant negative mechanism of Presenilin-1 mutations in FAD

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):12635-12637. doi: 10.1073/pnas.1717180114. Epub 2017 Nov 15.

Authors

Hirotaka Watanabe¹, Jie Shen²

Affiliations

¹ Department of Physiology, Keio University School of Medicine, Tokyo, 160-8582, Japan.
² Department of Neurology, Brigham & Women's Hospital, Program in Neuroscience, Harvard Medical School, Boston, MA 02115 jshen@bwh.harvard.edu.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Alzheimer Disease
Amyloid beta-Protein Precursor / genetics
Flavin-Adenine Dinucleotide*
Mutation
Presenilin-1 / genetics*
Presenilin-2

Substances

Amyloid beta-Protein Precursor
Presenilin-1
Presenilin-2
Flavin-Adenine Dinucleotide

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