Deep brain stimulation: custom-made silicone-coated pulse-generator implantation after allergic reaction to generator compounds

Acta Neurochir (Wien). 2018 Feb;160(2):385-387. doi: 10.1007/s00701-017-3373-z. Epub 2017 Nov 7.

Abstract

Deep brain stimulation for Parkinson's disease has become an established treatment option in recent years. The method and its application in clinical practice has proved to be safe and effective. Nevertheless, procedure-related and hardware-related complications occur. We present a rare case of a patient with an allergic reaction to the impulse generator. The patient suffered from delayed wound-healing deficits with several wound revisions and generator repositionings. After diagnosis of an allergic reaction to components of the generator, a custom-made silicon-coated model was implanted. Hereafter, no wound healing-deficit occurred throughout long-term follow-up. Allergic reaction to hardware components may lead to wound-healing deficits. In such cases, custom-made silicon-coated models may be an effective treatment option.

Keywords: Allergic reaction; Deep brain stimulation; Parkinson’s disease; Silicone-coated pulse generator.

Publication types

  • Case Reports

MeSH terms

  • Deep Brain Stimulation / adverse effects*
  • Deep Brain Stimulation / instrumentation
  • Deep Brain Stimulation / methods
  • Electrodes, Implanted / adverse effects*
  • Electrodes, Implanted / standards
  • Humans
  • Hypersensitivity / etiology*
  • Male
  • Middle Aged
  • Parkinson Disease / surgery*
  • Postoperative Complications / etiology*
  • Silicones

Substances

  • Silicones