Clinical significance of SH2B3 (LNK) expression in paediatric B-cell precursor acute lymphoblastic leukaemia

Br J Haematol. 2018 Oct;183(2):327-330. doi: 10.1111/bjh.14981. Epub 2017 Oct 29.
No abstract available

Keywords: SH2B3 (LNK); biomarker; paediatric B-ALL; prognostic factor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Adolescent
  • Biomarkers, Tumor / biosynthesis*
  • Biomarkers, Tumor / genetics
  • Child
  • Child, Preschool
  • Female
  • Gene Expression
  • Humans
  • Infant
  • Intracellular Signaling Peptides and Proteins
  • Kaplan-Meier Estimate
  • Male
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Prognosis
  • Proteins / genetics
  • Proteins / metabolism*
  • RNA, Messenger / genetics
  • RNA, Neoplasm / genetics

Substances

  • Adaptor Proteins, Signal Transducing
  • Biomarkers, Tumor
  • Intracellular Signaling Peptides and Proteins
  • Proteins
  • RNA, Messenger
  • RNA, Neoplasm
  • SH2B3 protein, human