[Clinical features and surgical treatment effect of patients with cardiac cavernous hemangioma]

Zhonghua Xin Xue Guan Bing Za Zhi. 2017 Sep 24;45(9):786-790. doi: 10.3760/cma.j.issn.0253-3758.2017.09.011.
[Article in Chinese]

Abstract

Objective: To investigate the clinical features and surgical treatment effect of patients with cardiac cavernous hemangioma. Methods: Clinical data of 9 patients (5 male, aged from 4 to 53 years old) with cardiac cavernous hemangioma, who underwent surgical treatment from November 2002 to March 2015 and the diagnosis of cardiac cavernous hemangioma was confirmed by postoperative histological examination, were retrospectively analyzed. Effects of surgical treatment were analyzed. Results: Four patients were asymptomatic (heart murmur presented in 3 patients during physical examination). Three patients presented with palpitation, chest distress, and short of breath. One patient presented with epigastric discomfort and another patient presented with intermittent fever for more than 10 months. ST and T wave changes of electrocardiogram were found in 2 patients, cardiac mass was detected in the right heart chamber in 5 patients by echocardiography, and no cardiac mass was detected the rest 4 patients. Cardiac masses were resected en bloc, then the adjacent tissues were repaired in 7 patients, and mass was partially resected due to the involvement with adjacent heart structure. No cardiac mass was found during operation in 1 case, impaired mitral valve structure was excised and postoperative pathologically confirmed as cardiac valve cavernous angioma on the excised mitral valve structure. No signs of recurrence or enlargement of cardiac cavernous hemangioma were found during the 11(10, 11)years follow up. Conclusions: There is no specific clinical feature for patients with cardiac cavernous hemangioma. It is difficult to detect the cardiac valve cavernous angioma by echocardiography before surgery. Individualized surgical treatment is associated with good clinical outcome in this patient cohort. However, the clinical features and surgical treatment effect of patients with cardiac cavernous hemangioma still need to investigate in large sample trial.

目的: 探讨心脏海绵状血管瘤的临床表现及外科手术疗效。 方法: 回顾性分析2002年11月至2015年3月在阜外医院行外科手术并经病理确诊的9例心脏海绵状血管瘤的临床资料。其中,男性5例,女性4例,年龄4~53岁。总结患者的临床特征,并分析外科手术的治疗效果。 结果: 9例心脏海绵状血管瘤患者中,无症状4例(体检发现心脏杂音3例),出现心悸、胸闷和气短3例,上腹不适1例,间断发热1例。心电图出现ST段或T波改变2例。超声心动图显示右心系统占位5例,其余4例患者的超声心动图未显示肿块影像。对其中7例患者行心脏海绵状血管瘤完整切除术并修补毗邻结构;1例患者行心脏海绵状血管瘤部分切除术;另外1例患者术中未发现肿物,切除的二尖瓣病变术后病理诊断为海绵状血管瘤。随访时间中位数为11(10,11)年,随访期间无肿物复发及心脏海绵状血管瘤部分切除后肿物增大。 结论: 心脏海绵状血管瘤无特异性临床表现,术前超声心动图难以发现瓣膜海绵状血管瘤。个体化手术治疗效果好,患者预后良好。但是,心脏海绵状血管瘤的临床表现及外科手术疗效尚需大样本试验的证实。.

Keywords: Cardiac surgical procedures; Hemangioma, cavernous; Treatment outcome.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Heart Neoplasms* / diagnosis
  • Heart Neoplasms* / surgery
  • Hemangioma, Cavernous* / diagnostic imaging
  • Hemangioma, Cavernous* / surgery
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve
  • Neoplasm Recurrence, Local*
  • Retrospective Studies
  • Young Adult